The Spanish champions suffered a 2-0 loss at Granada on Saturday night to stay in eighth position in the table – one spot and one point behind Villarreal, who have made a solid start to the 2019-20 campaign.
Barca’s loss at Granada on Saturday means the Spanish champions have made their worst start to a league season for 25 years and Chukwueze, who has scored once and provided an assist in four La Liga games, will be looking forward to adding to his tally in the encounter.
The last clash between Villarreal and Barca finished 4-4 at the Estadio de la Ceramica last season with the 20-year-old a thorn in the flesh of the Catalan giants, scoring one and providing an assist in the eight-goal thriller.
Should Chukwueze score a goal, it will be his 10th for Villarreal in 43 games (seventh La Liga goal in 31 games) since he broke into the first team.
Elsewhere, Ramon Azeez will be looking to build on his impressive start in La Liga this season, when Granada travel to the José Zorrilla Stadium, to face Real Valladolid.
Azeez equaled his best goal tally of two in the La Liga this season after scoring barely two minutes as Granada shocked Barcelona with a 2-0 win on Saturday.